Tyson Dawson
Tyson Dawson is a PhD student in the Genomics and Bioinformatics program of the Institute for Biomedical Sciences. Tyson is interested in the role of viruses in human transcriptional response. Tyson studies both exogenous viruses like SARS-CoV-2 and endogenous retroviruses, remnants of ancient viral infections that infected human ancestors millions of years ago and which may drive human diseases like lupus and Alzheimer's disease.
Tyson's Publications
1. Rahnavard A, Dawson T, Clement R, Stearrett N, Pérez-Losada M, Crandall KA. Epidemiological associations with genomic variation in SARS-CoV-2. Sci Rep. 2021 Nov 26;11(1):23023. PubMed PMID: 34837008.
2. Stearrett N, Dawson T, Rahnavard A, Bachali P, Bendall ML, Zeng C, Caricchio R, Pérez-Losada M, Grammer AC, Lipsky PE, Crandall KA. Expression of Human Endogenous Retroviruses in Systemic Lupus Erythematosus: Multiomic Integration With Gene Expression. Front Immunol. 2021;12:661437. PubMed Central PMCID: PMC8112243.
3. Cui Y, Cheng X, Chen Q, Song B, Chiu A, Gao Y, Dawson T, Chao L, Zhang W, Li D, Zeng Z, Yu J, Li Z, Fei T, Peng S, Li W. CRISP-view: a database of functional genetic screens spanning multiple phenotypes. Nucleic Acids Res. 2021 Jan 8;49(D1):D848-D854. PubMed Central PMCID: PMC7778972.
Images from Research
I aim to integrate gene and HERV expression data from lupus patients to uncover roles for HERVs in this disease. HERV expression may also be useful for subtyping lupus patients.
Samples were collected from nasal swabs of COVID-19 positive patients in the state of New Jersey. Viral genome, bacterial microbiome, and human transcriptome data were subsequently analyzed and integrated.
Phylogram of SARS-CoV-2 sequences annotated with patient metadata
I aim to integrate gene and HERV expression data from lupus patients to uncover roles for HERVs in this disease. HERV expression may also be useful for subtyping lupus patients.
Video About Lupus Research
I'm always looking for new and exciting opportunities. Let's connect!
